An American couple, Dr. Shane Brown and his wife, June, go to Paris, supposedly for their honeymoon. In reality, Shane has travelled to Paris to hunt down neuroscientist Dr. Léo Sémeneau and his wife, Coré, whom he once knew and was obsessed with. Despite having once had a prolific career, Léo is now working as a General practitioner to keep a low profile. He locks Coré up in their house every day but she occasionally manages to escape and violently murder men. To protect her, Léo buries the bodies. A couple of men who have been casing the Sémeneau home eventually break in where one of them finds Coré in a boarded up room. After she seduces him, they start to have sex, but she violently bites him to death, ripping out his tongue with her teeth.